BDBM683804 (6S,8R)-6-(5-((1-(3-fluoropropane)azetidin-3-yl)amino)pyridin-2-yl)-8-methyl-7-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydroxazolo[5,4-f]isoquinolin-2(3H)-one ::US20240217988, Example 26

SMILES C[C@@H]1Cc2c(ccc3[nH]c(=O)oc23)[C@H](N1CC(F)(F)F)c1ccc(NC2CN(CCCF)C2)cn1

InChI Key InChIKey=FFJIERGXVXIACP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 683804   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
Shenzhen Forward Pharmaceuticals Co.

US Patent
LigandPNGBDBM683804(US20240217988, Example 26 | (6S,8R)-6-(5-((1-(3-fl...)
Affinity DataIC50: 58.4nMAssay Description:1x Tris-HCl (Sigma, PHG0002) protein buffer was prepared and mixed for later use. The compound to be detected was prepared into a stock solution with...More data for this Ligand-Target Pair
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Date in BDB:
10/11/2024
Entry Details
US Patent