BDBM683805 (6S,8R)-6-(4-(((S)-1-(3-fluoropropyl)pyrrolidin-3-yl)oxy)-2-methoxyphenyl)-8-methyl-7-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydroxazolo[5,4-f]isoquinolin-2(3H)-one ::US20240217988, Example 30

SMILES COc1cc(O[C@H]2CCN(CCCF)C2)ccc1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1ccc1[nH]c(=O)oc21

InChI Key InChIKey=YDBODRYRYOFBAE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 683805   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
Shenzhen Forward Pharmaceuticals Co.

US Patent
LigandPNGBDBM683805(US20240217988, Example 30 | (6S,8R)-6-(4-(((S)-1-(...)
Affinity DataIC50: 8.85nMAssay Description:1x Tris-HCl (Sigma, PHG0002) protein buffer was prepared and mixed for later use. The compound to be detected was prepared into a stock solution with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent