BDBM683809 (6S,8R)-6-(4-((1-(3-fluoropropyl)azetidin-3-yl)amino)-2-methoxy-6-fluoro-phenyl)-8-methyl-7-(2,2,2-trifluoroethyl)-6,7,8,9-6,7,8,9-tetrahydrooxazolo[5,4-f]isoquinolin-2(3H)-one ::US20240217988, Example 34

SMILES COc1cc(NC2CN(CCCF)C2)cc(F)c1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1ccc1[nH]c(=O)oc21

InChI Key InChIKey=ACSBKCQZVYVOPN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 683809   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
Shenzhen Forward Pharmaceuticals Co.

US Patent
LigandPNGBDBM683809(US20240217988, Example 34 | (6S,8R)-6-(4-((1-(3-fl...)
Affinity DataIC50: 19.4nMAssay Description:1x Tris-HCl (Sigma, PHG0002) protein buffer was prepared and mixed for later use. The compound to be detected was prepared into a stock solution with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent