BDBM684520 US12030872, Example 7.3

SMILES CC1(COC1)N1CCC(CC1)c1cc2n(ncc2cc1Cl)-c1cnn(c1)C1CC1

InChI Key InChIKey=KOGPQINACYFZMH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 684520   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM684520(US12030872, Example 7.3)
Affinity DataIC50: 1.60nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM684520(US12030872, Example 7.3)
Affinity DataIC50: 67nMAssay Description:Inhibition of LRRK2 in human PBMCs assessed as Ser935 dephosphorylation incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed