BDBM684600 Preparation of 7-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-1-(4-(1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl)benzyl)-2,3-dihydro-1H-pyrido[3,4-b][1,4]oxazine ::US20240226107, Compound 3

SMILES COc1ncnc(C2CC2)c1-c1cc2N(Cc3ccc(cc3)-c3nc(cn3C)C(F)(F)F)CCOc2cn1

InChI Key InChIKey=USBNVEQHPQZHJT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684600   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM684600(US20240226107, Compound 3 | Preparation of 7-(4-cy...)
Affinity DataIC50: 21.3nMAssay Description:Each compound to be tested was dissolved with DMSO to 10 mM. The compound and pure DMSO (with a total volume of 50 nL) were loaded to each well of th...More data for this Ligand-Target Pair
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Date in BDB:
10/22/2024
Entry Details
US Patent