BDBM684631 Preparation of 2-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-5-methyl-8-(3-fluoro-4-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzyl)-7,8-dihydropteridin-6(5H)-one ::US20240226107, Compound 44

SMILES COc1ncnc(C2CC2)c1-c1ncc2N(C)C(=O)CN(Cc3ccc(c(F)c3)-n3nc(cc3C)C(F)(F)F)c2n1

InChI Key InChIKey=PQGUVYIPCXSOPK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684631   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM684631(US20240226107, Compound 44 | Preparation of 2-(4-c...)
Affinity DataIC50: 13.9nMAssay Description:Each compound to be tested was dissolved with DMSO to 10 mM. The compound and pure DMSO (with a total volume of 50 nL) were loaded to each well of th...More data for this Ligand-Target Pair
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Date in BDB:
10/22/2024
Entry Details
US Patent