BDBM684649 Preparation of 2-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-6-methyl-8-(4-(1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl)benzyl)pteridin-7(8H)-one ::US20240226107, Compound 61

SMILES COc1ncnc(C2CC2)c1-c1ncc2nc(C)c(=O)n(Cc3ccc(cc3)-c3nc(cn3C)C(F)(F)F)c2n1

InChI Key InChIKey=NZVYUSKYAJHTQU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684649   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM684649(US20240226107, Compound 61 | Preparation of 2-(4-c...)
Affinity DataIC50: 36.3nMAssay Description:Each compound to be tested was dissolved with DMSO to 10 mM. The compound and pure DMSO (with a total volume of 50 nL) were loaded to each well of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent