BDBM684671 Hemitriethylamine ((2R,3S,5R)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-2-ethynyl-3-hydroxytetrahydrothiophen-2-yl)methyl triphosphate::US20240226130, Compound 8

SMILES Nc1nc(=O)n(cc1F)[C@H]1C[C@H](O)[C@@](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)(S1)C#C

InChI Key InChIKey=YHOCANFFHHFNLR-UHFFFAOYSA-J

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 684671   

TargetGag-Pol polyprotein(HIV-1)
Gilead Sciences

US Patent
LigandPNGBDBM684671(US20240226130, Compound 8 | Hemitriethylamine ((2R...)
Affinity DataIC50: 100nMAssay Description:The RT IC50 filter binding assay utilized a synthetic D19/D78mer annealed primer template complex prepared by incubating 50 μM of 19-mer [5̸...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetGag-Pol polyprotein(HIV-1)
Gilead Sciences

US Patent
LigandPNGBDBM684671(US20240226130, Compound 8 | Hemitriethylamine ((2R...)
Affinity DataIC50: 210nMAssay Description:The RT IC50 filter binding assay utilized a synthetic D19/D78mer annealed primer template complex prepared by incubating 50 μM of 19-mer [5̸...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent