BDBM684684 US20240228486, Compound 2.4

SMILES CCc1nc2ccc(cc2[nH]c1=O)S(=O)(=O)N1CCN(CC1)c1ccc(nc1)C(=O)NC

InChI Key InChIKey=SMEZVTQZPIXSPT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 684684   

TargetPoly [ADP-ribose] polymerase 2(Human)
Enliven

US Patent
LigandPNGBDBM684684(US20240228486, Compound 2.4)
Affinity DataIC50: 23.9nMAssay Description:Compounds were dissolved and 4-fold serially diluted in DMSO. Compounds were transferred by an Echo to the assay plate to reach final concentrations ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Enliven

US Patent
LigandPNGBDBM684684(US20240228486, Compound 2.4)
Affinity DataIC50: 890nMAssay Description:Compounds were dissolved and 4-fold serially diluted in DMSO. Compounds were transferred by an Echo to the assay plate to reach final concentrations ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Enliven

US Patent
LigandPNGBDBM684684(US20240228486, Compound 2.4)
Affinity DataIC50: 890nMAssay Description:Compounds were dissolved and 4-fold serially diluted in DMSO. Compounds were transferred by an Echo to the assay plate to reach final concentrations ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent