BDBM684732 3-(1H-imidazol-2-yl)-4-(methylamino)-1-phenyl-7-(trifluoromethyl)-1,8-naphthyridin-2(1H)-one::US20240228491, Example 8

SMILES CNc1c(-c2ncc[nH]2)c(=O)n(-c2ccccc2)c2nc(ccc12)C(F)(F)F

InChI Key InChIKey=AWPXVZLNHARINF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684732   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM684732(US20240228491, Example 8 | 3-(1H-imidazol-2-yl)-4-...)
Affinity DataIC50: 8.70nMAssay Description:The specific steps were as follows: The compounds having the test starling concentration of 1 uM or 10 uM were diluted into 10 concentration points i...More data for this Ligand-Target Pair
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Date in BDB:
10/22/2024
Entry Details
US Patent