BDBM684770 1-((6-(3- aminopyrrolidin-1- yl)pyridin-3- yl)methyl)-3-(4-(2-(4- methoxyphenyl) propan-2-yl)thiazol-2- yl)urea::US20240226094, Compound A186

SMILES COc1ccc(cc1)C(C)(C)c1cnc(NC(=O)NCc2ccc(nc2)N2CCC(N)C2)s1

InChI Key InChIKey=PWFBDYFLHUNQTR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684770   

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandPNGBDBM684770(1-((6-(3- aminopyrrolidin-1- yl)pyridin-3- yl)meth...)
Affinity DataIC50: 19nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent