BDBM684771 US20240228491, Example 48

SMILES COCCn1cc2cc(ccc2n1)-c1c(N)c2ccc(nc2n(-c2ccc(Cl)cc2)c1=O)C(F)(F)F

InChI Key InChIKey=QETBHDMMXPETHS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684771   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Scinnohub Pharmaceutical

US Patent
LigandPNGBDBM684771(US20240228491, Example 48)
Affinity DataIC50: 16.1nMAssay Description:The specific steps were as follows: The compounds having the test starling concentration of 1 uM or 10 uM were diluted into 10 concentration points i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent