BDBM684782 1-(4-((2- aminoethyl)amino)-3- fluorobenzyl)-3-(4-(2- (4- bromophenyl)propan- 2-yl)thiazol-2-yl)urea::US20240226094, Compound A198

SMILES CC(C)(c1cnc(NC(=O)NCc2ccc(NCCN)c(F)c2)s1)c1ccc(Br)cc1

InChI Key InChIKey=LAYLGMGABDYGMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684782   

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandPNGBDBM684782(1-(4-((2- aminoethyl)amino)-3- fluorobenzyl)-3-(4-...)
Affinity DataIC50: 18nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent