BDBM684797 US20240228491, Example 72

SMILES CN(C)CCn1cc2cc(ccc2n1)-c1c(N)c2ccc(nc2n(-c2ccc(Cl)cc2)c1=O)C(F)(F)F

InChI Key InChIKey=FNJQMUUGQSXECY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684797   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM684797(US20240228491, Example 72)
Affinity DataIC50: 16.5nMAssay Description:The specific steps were as follows: The compounds having the test starling concentration of 1 uM or 10 uM were diluted into 10 concentration points i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent