BDBM684950 2-(exo-3- amino-9- azabicyclo [3.3.1] nonan-9- yl)-5-(4- chloro-2- methyl-2H- indazol- 5-yl)-3- methyl-3,7- dihydro- 4H-pyrrolo [2,3-d]pyri- midin-4- one::US12037345, Example 36

SMILES Cn1cc2c(Cl)c(ccc2n1)-c1c[nH]c2nc(N3[C@H]4CCC[C@@H]3C[C@@H](N)C4)n(C)c(=O)c12

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684950   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM684950(US12037345, Example 36 | 2-(exo-3- amino-9- azabic...)
Affinity DataIC50: 5.5nMAssay Description:SHP2 activity was monitored by measuring the conversion of the surrogate substrate 6,8-difluoromethylumbelliferyl phosphate (DiFMUP) to the fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2024
Entry Details
US Patent