BDBM685067 N-(4-(2-(4-chlorophenyl)but- 3-yn-2-yl)thiazol-2- yl)acetamide::US20240226094, Compound D004

SMILES CC(=O)Nc1nc(cs1)C(C)(C#C)c1ccc(Cl)cc1

InChI Key InChIKey=PTACHOHDVUVNSJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 685067   

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandPNGBDBM685067(N-(4-(2-(4-chlorophenyl)but- 3-yn-2-yl)thiazol-2- ...)
Affinity DataIC50: 18nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandPNGBDBM685067(N-(4-(2-(4-chlorophenyl)but- 3-yn-2-yl)thiazol-2- ...)
Affinity DataIC50: 18nMAssay Description:In brief, dose-response studies were performed in 384-well assay plates. Each well contained 0.1 mg TIFA, ALPK1 (2 nM final concentration in reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent