BDBM685249 2-(benzotriazol-1-yl)-N-[(3-chloro-2-fluoro-phenyl)methyl]-N-[4-(1H-imidazol-4-yl)phenyl]acetamide::US20240239772, Compound 84

SMILES Fc1c(Cl)cccc1CN(C(=O)Cn1nnc2ccccc12)c1ccc(cc1)-c1c[nH]cn1

InChI Key InChIKey=RFXNDCITBBUVHI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685249   

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandPNGBDBM685249(US20240239772, Compound 84 | 2-(benzotriazol-1-yl)...)
Affinity DataIC50: 230nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent