BDBM685256 2-(benzotriazol-1-yl)-N-[(3,5-difluorophenyl)methyl]-N-[4-(2,5-dihydro-1H-pyrrol-3-yl)phenyl]acetamide::US20240239772, Compound 91

SMILES Fc1cc(F)cc(CN(C(=O)Cn2nnc3ccccc23)c2ccc(cc2)C2=CCNC2)c1

InChI Key InChIKey=PFNXANUNHYCYKT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685256   

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandPNGBDBM685256(US20240239772, Compound 91 | 2-(benzotriazol-1-yl)...)
Affinity DataIC50: 130nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent