BDBM685658 US20240239813, Compound 16a

SMILES CN(C)CC1(COc2nc(N3CCC[C@](C)(O)C3)c3cnc(c(F)c3n2)-c2cc(N)cc(Cl)c2C(F)(F)F)CC1

InChI Key InChIKey=JIXKEWHTWQRQCQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685658   

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandPNGBDBM685658(US20240239813, Compound 16a)
Affinity DataIC50: 385nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent