BDBM685688 US20240239813, Compound 31a

SMILES CCc1c(F)ccc2cc(O)cc(-c3ncc4c(nc(OCC5(CC(N)=O)CC5)nc4c3F)N3CCC[C@]4(CCO4)C3)c12

InChI Key InChIKey=ZJAYUFSUNZDPAC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685688   

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandPNGBDBM685688(US20240239813, Compound 31a)
Affinity DataIC50: 518nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent