BDBM685692 US20240239813, Compound 33a

SMILES CCc1c(F)ccc2cc(O)cc(-c3ncc4c(nc(OCC5(CN6CCC(CC6)C(O)=O)CC5)nc4c3F)N3CCC[C@]4(CCO4)C3)c12

InChI Key InChIKey=COMHZPKFGCYVPD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685692   

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandPNGBDBM685692(US20240239813, Compound 33a)
Affinity DataIC50: 10.3nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent