BDBM685877 US12043625, Example 2.06

SMILES CO[C@@]1(CCS(=O)(=O)C[C@@H]1C)c1cc(Cl)cnc1O[C@H]1C[C@H](N(C1)c1nc(nc2c3ccccc3oc12)C(F)F)C(O)=O

InChI Key InChIKey=LEYHPZHFBYEBBZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685877   

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM685877(US12043625, Example 2.06)
Affinity DataIC50: 8nMAssay Description:PKC-theta and PKC-delta biochemical activities were measured using the PKC-theta HTRF KinEASEkit kit, according to manufacturer's instructions (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2024
Entry Details
US Patent