BDBM685894 US12043625, Example 3.03

SMILES COc1cc(c(F)cn1)-c1cnc(O[C@H]2C[C@H](N(C2)c2nc(nc3c4ccccc4oc23)C(F)F)C(O)=O)c(c1)[C@@]1(F)CCN(C[C@@H]1C)C(C)=O

InChI Key InChIKey=HQXIDDDOICQENU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685894   

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM685894(US12043625, Example 3.03)
Affinity DataIC50: 12nMAssay Description:PKC-theta and PKC-delta biochemical activities were measured using the PKC-theta HTRF KinEASEkit kit, according to manufacturer's instructions (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2024
Entry Details
US Patent