BDBM686233 US20240245694, Example 9

SMILES C[C@@H]1C[C@H](C(=O)Nc2ccc(C(F)(F)F)cc2Cl)n2c1c(N1CCN(C(=O)c3c(O)ccc4nccn34)CC1)c(=O)n1nc(C3=CCOCC3)nc21

InChI Key InChIKey=QRWPBNGDVWHCFN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686233   

LigandChemical structure of BindingDB Monomer ID 686233BDBM686233(US20240245694, Example 9)
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent