BDBM686240 US20240245694, Example 14C

SMILES Cc1ncnc(C(=O)N2CCN(c3c4n(c5nc(C6=CCOCC6)nn5c3=O)[C@@H](C(=O)Nc3ccc(C(F)(F)F)cc3Cl)C[C@@H]4C)CC2)c1O

InChI Key InChIKey=HFBDUGGMEDJGJD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686240   

LigandChemical structure of BindingDB Monomer ID 686240BDBM686240(US20240245694, Example 14C)
Affinity DataIC50: 100nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent