BDBM686379 US20240246932, Example 48A

SMILES C[C@H]1N(CCNC1=O)C(=O)N[C@H](c1cnc(OCC(F)(F)F)c(F)c1)c1ccc(F)c(n1)C(F)(F)F

InChI Key InChIKey=FGEVABSSBYCVTD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686379   

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686379(US20240246932, Example 48A)
Affinity DataIC50: 4.78nMAssay Description:NaV1.5 current measurements on Qube were obtained as follows: NaV1.5 currents were elicited with a 20 second 3 Hertz pulse train in the control condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent