BDBM686392 US20240246932, Example 54B

SMILES Fc1cc(ccc1Cl)[C@@H](NC(=O)N1CCNC(=O)C1)c1ccc(F)c(n1)C(F)(F)F

InChI Key InChIKey=ZCDTWBIFMQSWDU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686392   

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686392(US20240246932, Example 54B)
Affinity DataIC50: 4.14nMAssay Description:NaV1.5 current measurements on Qube were obtained as follows: NaV1.5 currents were elicited with a 20 second 3 Hertz pulse train in the control condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent