BDBM686408 US20240246932, Example 63A

SMILES C[C@H]1N(CCNC1=O)C(=O)N[C@@H](c1cnn(c1)C(F)(F)F)c1ccc(OC(F)(F)F)c(Cl)c1

InChI Key InChIKey=IXIOFWMDZZPTKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686408   

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686408(US20240246932, Example 63A)
Affinity DataIC50: 1.12nMAssay Description:NaV1.5 current measurements on Qube were obtained as follows: NaV1.5 currents were elicited with a 20 second 3 Hertz pulse train in the control condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent