BDBM686439 US20240246932, Example 78B

SMILES Fc1ccc([C@H](NC(=O)N2CCNC(=O)C2)c2ccc(Cl)c(n2)C(F)(F)F)c(F)c1Cl

InChI Key InChIKey=SQLCALKFSLCUTA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686439   

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686439(US20240246932, Example 78B)
Affinity DataIC50: 3.54nMAssay Description:NaV1.5 current measurements on Qube were obtained as follows: NaV1.5 currents were elicited with a 20 second 3 Hertz pulse train in the control condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent