BDBM686493 3-(1-oxo-5-(((1S,2S)-2-(4- phenylpiperidin-1- yl)cyclopentyl)oxy)isoindolin-2- yl)piperidine-2,6-dione::US20240246935, Example 72

SMILES O=C1N(Cc2cc(O[C@H]3CCC[C@@H]3N3CCC(CC3)c3ccccc3)ccc12)C1CCC(=O)NC1=O

InChI Key InChIKey=IOKRISVPYBIDNL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686493   

TargetProtein cereblon(Human)
Plexium, Inc.

US Patent
LigandPNGBDBM686493(US20240246935, Example 72 | 3-(1-oxo-5-(((1S,2S)-2...)
Affinity DataEC50:  7nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent