BDBM686531 4-(1-(2-((2-(2,6-dioxopiperidin-3- yl)-1-oxoisoindolin-5- yl)oxy)cyclopentyl)azetidin-3-yl)- 2-fluorobenzonitrile::US20240246935, Example 110

SMILES Fc1cc(ccc1C#N)C1CN(C1)C1CCCC1Oc1ccc2C(=O)N(Cc2c1)C1CCC(=O)NC1=O

InChI Key InChIKey=MJGIDMWRHLMUFQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686531   

TargetProtein cereblon(Human)
Plexium, Inc.

US Patent
LigandPNGBDBM686531(US20240246935, Example 110 | 4-(1-(2-((2-(2,6-diox...)
Affinity DataEC50:  19nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent