BDBM686546 3-(5-(((1S,2S)-2-(3-(3- methoxyphenyl)azetidin-1- yl)cyclohexyl)oxy)-1- oxoisoindolin-2-yl)piperidine-2,6- dione::US20240246935, Example 126

SMILES COc1cccc(c1)C1CN(C1)[C@H]1CCCC[C@@H]1Oc1ccc2C(=O)N(Cc2c1)C1CCC(=O)NC1=O

InChI Key InChIKey=UWHATYRSJFKQFU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686546   

TargetProtein cereblon(Human)
Plexium, Inc.

US Patent
LigandPNGBDBM686546(US20240246935, Example 126 | 3-(5-(((1S,2S)-2-(3-(...)
Affinity DataEC50:  5nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent