BDBM687758 Synthesis of N-(1-(3-methoxyphenyl)cyclopropyl)-6-(5-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide ::US20240246972, Compound 5

SMILES COc1cccc(c1)C1(CC1)NC(=O)c1cc2ccc(nc2[nH]1)-c1cn[nH]c1C

InChI Key InChIKey=KXPTUMLQPMMHGT-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 687758   

TargetRho-associated protein kinase 2(Human)
Avicenna Biosciences, Inc.

US Patent
LigandPNGBDBM687758(US20240246972, Compound 5 | Synthesis of N-(1-(3-m...)
Affinity DataIC50: 3.60nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Avicenna Biosciences, Inc.

US Patent
LigandPNGBDBM687758(US20240246972, Compound 5 | Synthesis of N-(1-(3-m...)
Affinity DataIC50: 18.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Avicenna Biosciences, Inc.

US Patent
LigandPNGBDBM687758(US20240246972, Compound 5 | Synthesis of N-(1-(3-m...)
Affinity DataIC50: 414nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit PRKX(Human)
Avicenna Biosciences, Inc.

US Patent
LigandPNGBDBM687758(US20240246972, Compound 5 | Synthesis of N-(1-(3-m...)
Affinity DataIC50: 614nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent