BDBM688063 US20240247015, Example 177

SMILES COCC(=O)N1CCP(=O)(CC1)c1cc2c(N[C@H](C)c3cccc(c3C)C(F)(F)F)nc(C)nc2cn1

InChI Key InChIKey=NLJLWVWCEZMZGX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 688063   

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
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US Patent
LigandPNGBDBM688063(US20240247015, Example 177)
Affinity DataIC50: 5.01nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent