BDBM688335 N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-5-(2,5-dimethylphenoxy)-2,2-dimethyl-pentanamide::US20240189287, Compound BNS822

SMILES Cc1ccc(C)c(OCCCC(C)(C)C(=O)NC2CCCOc3c2nn(c3-c2ccc(Cl)cc2)-c2ccccc2Cl)c1

InChI Key InChIKey=UPTIGDGIHKDTFJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 688335   

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688335(US20240189287, Compound BNS822 | N-[2-(2-chlorophe...)
Affinity DataKi:  1.40nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bionanosim (Bns

US Patent
LigandPNGBDBM688335(US20240189287, Compound BNS822 | N-[2-(2-chlorophe...)
Affinity DataIC50: 3.00E+4nMAssay Description:Cardiotoxicity potential of BNS808 and BNS822 on the hERG potassium channels was evaluated using the automated patch clamp method (SyncroPatch 384PE)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent