BDBM688354 (1R,9S,11S,34S)-4-chloro-1-fluoro-34-methyl-26,31-dioxo-8,15,30-trioxa-6,12,23,27,32,37-hexaazaheptacyclo[30.2.2.19,12.113,24.014,22..016,21]octatriaconta-2,4,6,13(37),14(22),16::US20240189315, Example 02

SMILES C[C@H]1CN2CC[C@]1(F)c1cc(Cl)cnc1O[C@H]1C[C@H](N(C1)c1nc(CC(=O)NCCOC2=O)nc2c1oc1ccccc21)C(O)=O

InChI Key InChIKey=QZROJAQFQRHUAY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 688354   

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688354(US20240189315, Example 02 | (1R,9S,11S,34S)-4-chlo...)
Affinity DataIC50: 17nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent