BDBM688398 BBL0100455::US20240189315, Compound 5, WO 2022/174012

SMILES Cc1nc(N2C[C@@H](CC(=O)Nc3ccc(cc3)-c3ccccc3)C[C@H]2C(O)=O)c2oc3ccccc3c2n1

InChI Key InChIKey=RBAMAUYCFHDUDI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 688398   

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688398(US20240189315, Compound 5, WO 2022/174012 | BBL010...)
Affinity DataIC50: 55nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent