BDBM688606 US20240190854, Example 101

SMILES CCc1cccc(C[C@H](N)c2ccccc2-c2noc3ccccc23)n1

InChI Key InChIKey=NAKGPHXZVYUPLW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 688606   

LigandPNGBDBM688606(US20240190854, Example 101)
Affinity DataIC50: 700nMAssay Description:PatchXpress 7000A Solutions are used to record HCN currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
King''s College London

US Patent
LigandPNGBDBM688606(US20240190854, Example 101)
Affinity DataIC50: 1.60E+3nMAssay Description:IonWorks Quattro Solutions are used to record hERG and nav1.5 currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
King''s College London

US Patent
LigandPNGBDBM688606(US20240190854, Example 101)
Affinity DataIC50: 2.80E+3nMAssay Description:IonWorks Quattro Solutions are used to record hERG and nav1.5 currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

LigandPNGBDBM688606(US20240190854, Example 101)
Affinity DataIC50: 1.31E+4nMAssay Description:PatchXpress 7000A Solutions are used to record HCN currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent