BDBM688747 (4R)-7,7-dimethyl-4-(1-(methylsulfonyl)spiro[indol-3,4′-piperidin]-1′-carbonyl)-6,9-dioxo-1-phenyl-2,10-dioxa-5,8-diazadodecan-11-yl 2-methylbutyrate::US20240190875, Example 12

SMILES CCC(C)C(=O)OC(C)OC(=O)NC(C)(C)C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC2(CN(c3ccccc23)S(C)(=O)=O)CC1

InChI Key InChIKey=CWTJWQZYCLYPBH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 688747   

TargetGrowth hormone secretagogue receptor type 1(Human)
Changchun Genescience Pharmaceutical Co.

US Patent
LigandPNGBDBM688747(US20240190875, Example 12 | (4R)-7,7-dimethyl-4-(1...)
Affinity DataEC50:  35.9nMAssay Description:This method was used to determine the agonism effect of the compound of the invention on the activity of human GHSR protein expressed in human GHSR/C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent