BDBM688751 (5-methyl-2-oxo-1,3-dioxacyclopenten-4-yl)methyl (R)-(1-((3-(benzoxy)-1-(1-(methylsulfonyl)spiro[indol-3,4′-piperdin]-1′-yl)-1-oxopropan-2-yl)amino)-2-methyl-1-oxopropan-2-yl)carbamate::US20240190875, Example 17

SMILES Cc1oc(=O)oc1COC(=O)NC(C)(C)C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC2(CN(c3ccccc23)S(C)(=O)=O)CC1

InChI Key InChIKey=WWWZXVZEKISHQI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 688751   

TargetGrowth hormone secretagogue receptor type 1(Human)
Changchun Genescience Pharmaceutical Co.

US Patent
LigandPNGBDBM688751(US20240190875, Example 17 | (5-methyl-2-oxo-1,3-di...)
Affinity DataEC50:  24.5nMAssay Description:This method was used to determine the agonism effect of the compound of the invention on the activity of human GHSR protein expressed in human GHSR/C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent