BDBM688752 (R)-3-((1-((3-(benzoxy)-1-(1-(methansulfonyl)spiro[indolin-3,4′-piperidin]-1′-yl)-1-oxopropan-2-yl)amino)-2-methyl-1-oxopropan-2-yl)carbamoyl)-1-methylpyridin-1-ium Quaternary Ammonium salt::US20240190875, Example 18

SMILES C[n+]1cccc(c1)C(=O)NC(C)(C)C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC2(CN(c3ccccc23)S(C)(=O)=O)CC1

InChI Key InChIKey=HRWYNBKQXXRYTA-UHFFFAOYSA-O

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 688752   

TargetGrowth hormone secretagogue receptor type 1(Human)
Changchun Genescience Pharmaceutical Co.

US Patent
LigandPNGBDBM688752(US20240190875, Example 18 | (R)-3-((1-((3-(benzoxy...)
Affinity DataEC50:  15.1nMAssay Description:This method was used to determine the agonism effect of the compound of the invention on the activity of human GHSR protein expressed in human GHSR/C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent