BDBM688753 (R,Z)-N-(3-(benzoxy)-1-(1-(methylsulfonyl)spiro[indol-3,4′-piperidin]-1′-yl)-1-oxopropan-2-yl)-2-methyl-2-((4-oxopen-2-en-2-yl)amino)propionamide::US20240190875, Example 19

SMILES CC(=O)\C=C(\C)NC(C)(C)C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC2(CN(c3ccccc23)S(C)(=O)=O)CC1

InChI Key InChIKey=DMRFIZOSWOSWDC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 688753   

TargetGrowth hormone secretagogue receptor type 1(Human)
Changchun Genescience Pharmaceutical Co.

US Patent
LigandPNGBDBM688753(US20240190875, Example 19 | (R,Z)-N-(3-(benzoxy)-1...)
Affinity DataEC50:  24.3nMAssay Description:This method was used to determine the agonism effect of the compound of the invention on the activity of human GHSR protein expressed in human GHSR/C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent