BDBM688754 (4R)-7,7-dimethyl-4-(1-(methylsulfonyl)spiro[indolin-3,4′-piperidin]-1′-carbonyl)-6,9-dioxo-1-phenyl-2,10-dioxa-5,8-diazadodecan-11-yl Pivalate::US20240190875, Example 20

SMILES CC(OC(=O)NC(C)(C)C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC2(CN(c3ccccc23)S(C)(=O)=O)CC1)OC(=O)C(C)(C)C

InChI Key InChIKey=KPWSNUIFQPKYGR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 688754   

TargetGrowth hormone secretagogue receptor type 1(Human)
Changchun Genescience Pharmaceutical Co.

US Patent
LigandPNGBDBM688754(US20240190875, Example 20 | (4R)-7,7-dimethyl-4-(1...)
Affinity DataEC50:  37.7nMAssay Description:This method was used to determine the agonism effect of the compound of the invention on the activity of human GHSR protein expressed in human GHSR/C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent