BDBM688755 (R)-5,5-dimethyl-8-(1-(methylsulfonyl)spiro[indolin-3,4′-piperidin]-1′-carbonyl)-3,6-dioxo-11-phenyl-2,10-dioxa-4,7-diazadodecyl Pivalate::US20240190875, Example 21

SMILES CC(C)(C)C(=O)OCOC(=O)NC(C)(C)C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC2(CN(c3ccccc23)S(C)(=O)=O)CC1

InChI Key InChIKey=VHTUWOATYLWKHR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 688755   

TargetGrowth hormone secretagogue receptor type 1(Human)
Changchun Genescience Pharmaceutical Co.

US Patent
LigandPNGBDBM688755(US20240190875, Example 21 | (R)-5,5-dimethyl-8-(1-...)
Affinity DataEC50:  18.3nMAssay Description:This method was used to determine the agonism effect of the compound of the invention on the activity of human GHSR protein expressed in human GHSR/C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent