BDBM688783 US20240190889, Example RE-C

SMILES C[C@@H]1N=C(c2c3CCCc3sc2-n2c(C)nnc12)c1c(F)cccc1F

InChI Key InChIKey=KFRCPAXRUYFZQC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 688783   

LigandPNGBDBM688783(US20240190889, Example RE-C)
Affinity DataKi:  2.59nMAssay Description:The affinity of compounds at GABAA γ1 subunit-containing receptors was measured by competition for [3H]RO7239181 (67.3 Ci/mmol: Roche) binding t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

LigandPNGBDBM688783(US20240190889, Example RE-C)
Affinity DataKi:  17.2nMAssay Description:The affinity of compounds at GABAA γ2 subunit-containing receptors was measured by competition for [3H]Flumazenil (81.1 Ci/mmol; Roche) binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

LigandPNGBDBM688783(US20240190889, Example RE-C)
Affinity DataKi:  20.4nMAssay Description:The affinity of compounds at GABAA γ1 subunit-containing receptors was measured by competition for [3H]RO7239181 (67.3 Ci/mmol: Roche) binding t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent