BDBM688785 (R)-3-(5-(ethoxymethyl)-2-vinylpyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-5

SMILES CCOCc1cnc(C=C)nc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1

InChI Key InChIKey=VAVIMUFNSVHOGU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 688785   

TargetMAP kinase-activated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM688785(US20240190890, Compound I-5 | (R)-3-(5-(ethoxymeth...)
Affinity DataIC50: 7nMAssay Description:Briefly, 10× stock solutions of MK2 (PV3317, from Life Technologies), 1.13X ATP (AS001A), and Sox conjugated peptide substrate, S/T3-Sox, (KZN1031) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent