BDBM689056 US20240190893, Compound 4

SMILES Cc1nn(C)c(C)c1-c1c(Cl)ccc2c3CCCOc4cc(CCc5cc(CS(=O)(=O)CCCn(c3C(O)=O)c12)nn5C)cc1cc(F)ccc41

InChI Key InChIKey=SNPFGRONLJFBPT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689056   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM689056(US20240190893, Compound 4)
Affinity DataKi:  0.251nMAssay Description:This assay evaluated inhibition of the BH3 domain: Mcl-1 interaction by measuring the displacement of Cy5-labeled BIM BH3 peptide (H2N (C/Cy5Mal) WIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent