BDBM689099 US20240190893, Compound 15

SMILES Cn1nc2CS(=O)CCCn3c(C(O)=O)c(CCCOc4cc(CCc1c2)cc1cc(F)ccc41)c1ccc(Cl)c(-c2cncnc2)c31

InChI Key InChIKey=NJTZEPYLTPWYPA-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689099   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM689099(US20240190893, Compound 15)
Affinity DataKi:  0.426nMAssay Description:This assay evaluated inhibition of the BH3 domain: Mcl-1 interaction by measuring the displacement of Cy5-labeled BIM BH3 peptide (H2N (C/Cy5Mal) WIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent