BDBM689185 N-(4-methyl-1,1-dioxo- thian-4-yl)-6-[[3-(2,2,2- trifluoroethoxy)-2- pyridyl]oxy]-1,3- benzoxazole-2- carboxamide::US20240254114, Example 2

SMILES CC1(CCS(=O)(=O)CC1)NC(=O)c1nc2ccc(Oc3ncccc3OCC(F)(F)F)cc2o1

InChI Key InChIKey=UCHWNJYSESGYSS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689185   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM689185(US20240254114, Example 2 | N-(4-methyl-1,1-dioxo- ...)
Affinity DataIC50: 47nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
US Patent