BDBM689211 6-((5-fluoro-3-(2,2,2- trifluoroethoxy)pyridin-2- yl)oxy)-1-methyl-N-(4-methyl- 1,1-dioxidotetrahydro-2H- thiopyran-4-yl)-1H- benzo[d]imidazole-2- carboxamide::US20240254114, Example 13

SMILES Cn1c(nc2ccc(Oc3ncc(F)cc3OCC(F)(F)F)cc12)C(=O)NC1(C)CCS(=O)(=O)CC1

InChI Key InChIKey=XJLRPXUGWRXYMC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689211   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM689211(US20240254114, Example 13 | 6-((5-fluoro-3-(2,2,2-...)
Affinity DataIC50: 1.70nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
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Date in BDB:
11/20/2024
Entry Details
US Patent